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Individuals addressed with flumazenil needs to be monitored for re-sedation, respiratory melancholy, and other residual benzodiazepine effects for an proper period immediately after treatment. The prescriber need to concentrate on a danger of seizure in association with flumazenil treatment, especially in prolonged-term benzodiazepine people and in cyclic antidepressant overdose. The complete flumazenil bundle insert need to be consulted before use.
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In addition, fatalities are claimed in patients who may have overdosed with a combination of only one benzodiazepine, such as alprazolam, and alcohol; Liquor levels seen in A few of these patients are already lessen than All those normally connected with alcohol-induced fatality.
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